Arizona State +2.5 3.3% play
The wrong team is favored here and Colorado has faced the weakest schedule of maybe any team. Their opponents are 1-16, and they have yet to play a top 50 pass defense or top 50 run defense, but they are about to face Arizona State who is both.
Arizona State is well coached and may be as balanced as any team in the country. Manny Wilkins is not turning the ball over at QB and he can run the ball as well. Wilkins ran for 95 yards in this matchup last year as Colorado gave up a season high 381 yards to Arizona STate. Arizona State 6.25 yards per carry in wins and 3.13 in losses will be the key. I think they can run in this game with Wilkins back there and the RB Eno Benjamin. Colorado has given up more than 5 yards per carry against two worse rushing offenses in Nebraska and UCLA. Nebraska's freshmen QB Martinez rushed for 117 yards.
For Arizona State's defense I feel like they can dominate. They are running a different defense that Colorado is not used to seeing in the 3-3-5. They are ranked 10th in the nation in sack %, and Colorado's offensive line is struggling to pass protect ranking 92nd. That's with facing teams who rank 116, 42, and 72 in getting to the QB. I think Arizona State is fully capable of dominating this game and winning by double digits.