The Indians are 29th in OPS vs. LHP as they face J.A. Happ whose numbers look bad on paper, but he's been solid at home in most of his games and carries a 3.89 XFIP. He should be able to have success against the Indians who are hitting just .219 and scoring 3.64 runs per 9 vs. LHP while posting a bullpen ERA of 5.13 on the road this year over a run higher than the Astros bullpen ERA.

Derek Lowe starts for the Indians and Carlos Lee is very familiar with the righty going 16-44 with 2 HR and a .364 average. Lowe has a 6.18 ERA in his 7 road starts and he faces an Astros team that's scoring nearly a run more at home than the Indians are on the road. Astros are also 36-15 in their last 51 inter league games as a favorite -110 to -150.